Stack Crusade loot bonuses for relics

Void Crusade map, bonus and secret missions, and Supreme reward area.

Before you go

Choose the Crusade color and inspect its map for bonus and optional mission branches.
Set a manageable difficulty and select only modifiers your build can clear.
Complete reachable bonus missions to add their loot-related benefits and earn potential key rewards.
Reveal secret missions only when their unlock conditions are available and the detour is reasonable.
Track lives and map progress after every mission; avoid stacking risk beyond your build’s capacity.
Collect fragments if available so end-room cache choices can support your gear target.
Finish at Supreme and inspect its loot and any keyed chests for relics and useful rolls.

Prioritize consistent completion over maximum modifiers; a failed run loses the opportunity to claim its final rewards.
Use fragments to direct keys toward a relevant cache instead of opening blindly.

Repeat whenever you have five shards of a color and want another loot-focused attempt. Relic drops and their rolls remain variable.

Treating bonuses as guaranteed relics: they improve loot conditions, not certainty.
Adding every optional mission regardless of difficulty: trim the route when lives or survivability fall.
Opening unrelated caches: use available information and keys for the gear goal.

Switch to a safer route if the next bonus mission threatens the run; stop farming when a useful relic meets your build’s need.

Sources & fact checks

Open a guide to find other locations and see what the item is used for.

Endgame loot

Optional and bonus missions can build Crusade loot bonuses that make a run more focused on higher-quality and rarer gear.