Boss and enemy farming
Repeat Zarpedon through the Eye of Helios chests
This route clarifies that the lasting farm is the treasure room, not repeatedly defeating the story boss.
Eye of Helios, followed by the treasure room beyond the Zarpedon encounter.
The Zarpedon kill is a one-time unlock for this loop. The post-fight chest room can be revisited by saving and quitting inside it, then reloading.
Stop when the chest drops no longer help your build or when you want to pursue a targeted Legendary elsewhere.
Open a guide to find other locations and see what the item is used for.
This route clarifies that the lasting farm is the treasure room, not repeatedly defeating the story boss.