Save the Eye of Helios room for repeated chests
After defeating Zarpedon, loot the treasure room and save and quit from inside it to refresh the chests.
The Pre-Sequel adds Moonstones and the Concordia Grinder to Borderlands’ boss and chest loops. The Eye of Helios treasure room can be reset after its story boss, while Iwajira is a repeatable Moonstone source and Guardian Hunter offers an unfinished mission wave farm. Grinding duplicate items can turn spare gear into a desired weapon class.
17 farming guides · PC / Global, base game and released DLC

Unlock requirements, costs and tips to help you get started.
After defeating Zarpedon, loot the treasure room and save and quit from inside it to refresh the chests.
Iwajira in Serenity’s Waste can provide Moonstones and a chance at the Thingy launcher, making the route useful for either goal.
For the Legendary recipe, the purple item sets the result’s weapon type. Moonstone Grind adds a Luneshine chance, so spend the currency when that tradeoff suits your goal.
Prioritize current Moonstone and targeted gear goals first, followed by repeatable general loot routes and Grinder progression.
Iwajira offers a repeatable boss kill with Moonstone and Legendary loot potential.
A repeatable boss route supplies Moonstones for upgrades, Moonstone chests, and special Grinder recipes.
Felicity combines a boss loot check with access to a chest room, including a Moonstone Chest.
This multi-part route combines chests, lockers, named enemies, and a repeatable reward interaction for broad loot hunting.
Tiny Destroyer has a chance to drop the Moonlight Saga, giving this named enemy a focused gear check within a broader map route.
EX Stalker provides a named-enemy chance for Celestial Vanquisher class mods during the Research and Development route.
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This multi-part route combines chests, lockers, named enemies, and a repeatable reward interaction for broad loot hunting.
Tiny Destroyer has a chance to drop the Moonlight Saga, giving this named enemy a focused gear check within a broader map route.
EX Stalker provides a named-enemy chance for Celestial Vanquisher class mods during the Research and Development route.
Torques and Badass Torques offer a chance at the Bonus Package during the Research and Development clear.
After activating the map’s four pressure pads, Benjamin Blue offers a shorter repeatable loot interaction.
The post-Zarpedon chest room provides a repeatable source of varied gear, ammunition, and saleable items.
Browse more guides in this category.
Iwajira offers a repeatable boss kill with Moonstone and Legendary loot potential.
Felicity combines a boss loot check with access to a chest room, including a Moonstone Chest.
This route clarifies that the lasting farm is the treasure room, not repeatedly defeating the story boss.
An unfinished mission objective allows repeated Guardian spawns for experience, cash, gear, and Moonstones.
Browse more guides in this category.
A repeatable boss route supplies Moonstones for upgrades, Moonstone chests, and special Grinder recipes.
Moonstone grinding spends currency to improve the rarity outcome and can add a Luneshine effect.
Sorting spare equipment into valid inputs turns otherwise unwanted drops into potential upgrades.
Browse more guides in this category.
The post-Zarpedon chests offer a repeatable broad gear refresh as your character advances.
Building currency first lets you choose special Grinder attempts without draining resources needed elsewhere.
Unlocking Janey Springs’ machine opens a permanent way to process spare equipment into new gear.
Recommended farming guides. Search by item, goal or location.
Iwajira offers a repeatable boss kill with Moonstone and Legendary loot potential.
A repeatable boss route supplies Moonstones for upgrades, Moonstone chests, and special Grinder recipes.
Felicity combines a boss loot check with access to a chest room, including a Moonstone Chest.
This multi-part route combines chests, lockers, named enemies, and a repeatable reward interaction for broad loot hunting.
Tiny Destroyer has a chance to drop the Moonlight Saga, giving this named enemy a focused gear check within a broader map route.
EX Stalker provides a named-enemy chance for Celestial Vanquisher class mods during the Research and Development route.
Torques and Badass Torques offer a chance at the Bonus Package during the Research and Development clear.
After activating the map’s four pressure pads, Benjamin Blue offers a shorter repeatable loot interaction.
The post-Zarpedon chest room provides a repeatable source of varied gear, ammunition, and saleable items.
This route clarifies that the lasting farm is the treasure room, not repeatedly defeating the story boss.
The post-Zarpedon chests offer a repeatable broad gear refresh as your character advances.
An unfinished mission objective allows repeated Guardian spawns for experience, cash, gear, and Moonstones.
The Grinder can convert spare high-rarity weapons into a random Legendary of a chosen weapon class.
Moonstone grinding spends currency to improve the rarity outcome and can add a Luneshine effect.
Sorting spare equipment into valid inputs turns otherwise unwanted drops into potential upgrades.
Building currency first lets you choose special Grinder attempts without draining resources needed elsewhere.
Unlocking Janey Springs’ machine opens a permanent way to process spare equipment into new gear.