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WHERE & HOW TO FARM

Target-farm Lair Boss Uniques

Map-marked Lair Boss lairs across Sanctuary.

SEE WHERE TO GO

Maps & farm layouts

1 map

Drag to pan. Zoom in to read labels and markers.

Gaping Crevasse entrance for Duriel. This location reference is from the original Sanctuary map; use the current guide and in-game boss panel for entry costs and rewards.
Gaping Crevasse entrance for Duriel. This location reference is from the original Sanctuary map; use the current guide and in-game boss panel for entry costs and rewards.

Before you go

Farming steps

  1. Open the map and inspect the Lair Boss entries and Unique pools.
  2. Confirm the item you want appears in the selected boss’s current pool.
  3. Check your inventory for the matching Hoard key and confirm Torment eligibility.
  4. Travel to the lair and progress through the encounter to the boss.
  5. Defeat the boss using a build suited to the fight and difficulty.
  6. Use the key on its Hoard and inspect the reward for your target.

Repeat, collect and use

Repeat the boss and Hoard loop while you have keys and the target remains useful. The Unique is not guaranteed per attempt; replenish keys through endgame activities.

Common mistakes

  • Farming a boss whose pool excludes the item: verify its current preview first.
  • Using a key as an entry item: defeat the boss, then open the Hoard.
  • Expecting every kill to drop the target: continue only while more attempts fit your goal and key supply.

When to stop or switch

Stop when you obtain the Unique or your remaining keys are better saved; farm another boss or return to key-producing activities.

Sources & fact checks

What you can get here

Open a guide to find other locations and see what the item is used for.