Boss-specific Unique pools focus repeated Lair Boss runs on items relevant to a build.
PC / Global, current expansion content where available
WHERE & HOW TO FARM
Where to farm
Map-marked Lair Boss lairs across Sanctuary.
Start by checking the lair’s current Unique pool, then spend time and keys only on a boss that can reward your target. Torment I or higher is required to claim Lair Boss Hoards. The key opens the reward after the fight; it does not start the encounter. Drops remain uncertain, so plan a repeatable supply route and treat each Hoard as another chance rather than a guaranteed item.
Gaping Crevasse entrance for Duriel. This location reference is from the original Sanctuary map; use the current guide and in-game boss panel for entry costs and rewards.
GET STARTED
How to farm
Before you go
Torment I or higher for Hoard claims.
The relevant Lair Key for the selected boss’s Hoard.
A desired Unique confirmed in that boss’s current pool.
Open the map and inspect the Lair Boss entries and Unique pools.
Confirm the item you want appears in the selected boss’s current pool.
Check your inventory for the matching Hoard key and confirm Torment eligibility.
Travel to the lair and progress through the encounter to the boss.
Defeat the boss using a build suited to the fight and difficulty.
Use the key on its Hoard and inspect the reward for your target.
Farming tips
In group play, each player needs their own key to claim a Hoard.
Keep a short target list so you can change bosses when your build needs change.
Repeat, collect and use
Repeat the boss and Hoard loop while you have keys and the target remains useful. The Unique is not guaranteed per attempt; replenish keys through endgame activities.
Common mistakes
Farming a boss whose pool excludes the item: verify its current preview first.
Using a key as an entry item: defeat the boss, then open the Hoard.
Expecting every kill to drop the target: continue only while more attempts fit your goal and key supply.
When to stop or switch
Stop when you obtain the Unique or your remaining keys are better saved; farm another boss or return to key-producing activities.
