WHERE & HOW TO FARM Where to farm Chaos Chamber encounter rooms, on walls after clearing an encounter; successful runes lead to a red portal after the normal final boss.
Inspect completed encounter rooms for colored wall runes. Solving a rune’s challenge contributes to unlocking optional secret-boss encounters after the regular final boss. These puzzles have limited attempts, so take them only when you can afford to spend attention and time on the extra challenge.
Before you go Finish the campaign and unlock the Chaos Chamber. Bring a build capable of handling optional boss fights. Be willing to skip a puzzle if the main run is already at risk. After clearing an encounter, scan nearby walls for an interactable yellow, blue or green rune. Activate a rune only when ready to attempt its puzzle. For yellow, destroy the spawned orb while staying clear of its moving light. For blue, guide the orb to its destination without hitting obstacles, then shoot it there. For green, shoot the spores marked with a purple glow as the challenge unfolds. Continue the regular run and defeat its final boss. If the rune challenges were successful, use the opened red portal to enter the optional secret encounter. Farming tips Keep the yellow light and blue route in view before firing or moving; failed attempts are limited. Prioritize finishing the ordinary run if a puzzle is consuming attempts or your build is low on resources. Repeat, collect and use Rune appearances are part of repeatable Chamber runs, but each puzzle attempt has limited chances within that run.
Common mistakes Treating every rune as mandatory: the secret route is optional, so skip it when needed. Shooting the blue orb before it reaches its destination: guide it safely first. Standing in the yellow light: avoid the beam while damaging the orb. When to stop or switch Skip further puzzles when their attempts are exhausted or the added encounter threatens completion of the main run.
REWARD DETAILS & CONDITIONS Sources & rewards All source types Farming route Farming priority Name A–Z Drop chance
Farming route Chaos Chamber encounter rooms, on walls after clearing an encounter; successful runes lead to a red portal after the normal final boss.
Finish the campaign and unlock the Chaos Chamber. Bring a build capable of handling optional boss fights. Be willing to skip a puzzle if the main run is already at risk. Rate not listed
Related guides More guides for gathering materials and making progress.
Find another guide Keep making progress in Tiny Tina’s Wonderlands.
