Annihilus comes from the separate Diablo Clone event, which requires a different trigger and encounter from Uber Tristram.
PC / Global, Reign of the Warlock content where available
WHERE & HOW TO FARM
Where to farm
An eligible online game after the Diablo Clone trigger; the Clone replaces a Super Unique monster in the world.
This is a conditional online event rather than a conventional boss you can repeatedly summon on demand. When Diablo Clone spawns in an eligible game, locate and defeat him, then collect the Annihilus Small Charm if it drops. Track event readiness through in-game notifications and mode availability.
Play an online mode where the Diablo Clone event is available.
Have the character and gear to defeat a powerful Hell encounter.
Be present in the game when the event notification confirms the spawn.
Monitor the in-game Diablo Clone notification in an eligible online game.
When the spawn is confirmed, check likely Super Unique locations you can reach safely.
Locate the replaced monster and engage Diablo Clone with your strongest reliable damage.
Avoid standing in dangerous attacks and use healing or repositioning as needed.
Defeat him and inspect the ground for Annihilus.
Identify the charm and compare its attributes, resistances, and experience bonus with your needs.
Farming tips
Annihilus and Hellfire Torch come from separate events; the Pandemonium chain does not produce Annihilus.
Do not spend time searching before the event notification; the spawn is conditional.
Repeat, collect and use
Limited by event triggers and mode availability; a new attempt requires another valid Clone spawn, and Annihilus is not assured by the route description.
Common mistakes
Confusing Uber Tristram with Diablo Clone; prepare for the separate event and trigger.
Assuming a spawn is active without the in-game notice; wait for confirmation before searching.
Entering the fight without Hell-ready defenses; use suitable gear and healing before engaging.
When to stop or switch
Stop after obtaining an Annihilus you want or when the event is inactive; return to regular farming until another eligible trigger occurs.